The Elsässer Lab at Karolinska Institutet

LABORATORY OF CHEMICAL AND SYNTHETIC SYSTEMS BIOLOGY

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Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
Generation of Amber Suppression Cell Lines Using CRISPR-Cas9
Dynamic antagonism between key repressive pathways maintains the placental epigenome
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation
Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation
Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43
Distinct transcription kinetics of pluripotent cell states
A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling
Genome-wide mapping of G-quadruplex structures with CUT&Tag

simon at elsaesserlab.org

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